AKT-INDUCED PHOSPHORYLATION OF N-COR AT SERINE 1450 CONTRIBUTES TO ITS MISFOLDED CONFORMATIONAL DEPENDENT LOSS (MCDL) IN ACUTE MYELOID LEUKEMIA OF THE M5 SUBTYPE.

The nuclear receptor co-repressor (N-CoR) is a key component of the generic co-repressor complex Astragalus that plays an important role in the control of cellular growth and differentiation.As shown by us recently, the growth suppressive function of N-CoR largely relies on its capacity to repress Flt3, a key regulator of cellular gorwth during nor

Disaster warning and surveillance systems have been widely applied to help the public be aware of an emergency.However, existing warning systems are unable to cooperate with household appliances or embedded controllers; that is, they cannot provide enough time for Bosch KSV36AW4PG Serie 6 A+++ Free Standing Fridge 346 Litres White preparedness and

Insect pest control is a key mechanism to give humans advantage over insects in competition for food resources.Bioinsecticides are highly virulent in target insects, can control their populations and prevent a sharp increase in their number.The bioinsecticide Virin HSK was created in FBRI SRC VB “Vector”.Helicoverpa zea single nuclear polyhedro

Background: Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disorder.The pathogenesis is unclear, but it is thought to be immune-mediated.The prognosis is favorable, with most children making a full recovery.Objectives: The present report analyzed different clinical presentations, response to treatment and outcome in a